Southern Medical Journal - Rapid Response

It is what we do not know that may hurt us most!

NOTE: The viewpoints presented in the prepared responses are solely the opinions of the authors and have not been peer-reviewed. The Southern Medical Journal is providing "Rapid Response" as a forum for thought and consideration of a variety of views but does not in any way endorse or support the viewpoints presented.

Please direct responses/comments to smjedit@etsu.edu.

PUBLISHED MANUSCRIPT

The Bone and Joint Decade 2000-2010 Task Force on Neck Pain and Its Associated Disorders: Executive Summary. Spine 2008: 33(4S)

SOLICITED RESPONSE(S)

Neck Pain and Its Associated Disorders: A Complex Conundrum, Dino Samartzis, DSc, PhD (C ), MSc, Dip EBHC, MRIPH,Francis H. Shen, MD - Posted March 25, 2008

PUBLISHED MANUSCRIPT

National Osteoporosis Foundation 2008 Clinician's Guide to Prevention and Treatment of Osteoporosis. Washington, DC: National Osteoporosis Foundation; 2008.

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New Guidelines for Prevention and Treatment of Osteoporosis, E. Michael Lewiecki, MD,Nelson. B. Watts, MD - Posted March 21, 2008

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Heart Failure in the 21st Century, Rajat Bhatt, MD - Posted March 5, 2008

PUBLISHED MANUSCRIPT

Digitalis: A Dangerous Drug in Atril Fibrillation? An Analysis of the SPORTIF III and V Data. Heart 2008; 94: 191-196.

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To Dig or Not to Dig: A Lethal Question in Atrial Fibrillation?, Juan Tamargo MD, PhD, FESC,José López-Sendón MD, PhD, FESC - Posted March 5, 2008

PUBLISHED MANUSCRIPT

Organizational Factors and Office Workers’ Health after the World Trade Center Terrorist Attacks: Long-term Physical Symptoms, Psychological Distress and Work-Productivity. J of Occ and Env M 2008;50:112-125.

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Understanding the Health Impact of the September 11th Attacks, E. Alison Holman, FNP, PhD - Posted February 21, 2008

PUBLISHED MANUSCRIPT

Practice Parameter: Treatment of Nervous System Lyme Disease (An Evidence-Based Review) Report on the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2007; 69:91-102.

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The American Academy of Neurology Lyme Guidelines: Through the Looking Glass. , Raphael B. Stricker, M.D.* ,Lorraine Johnson, J.D., M.B.A.* - Posted February 8, 2008

PUBLISHED MANUSCRIPT

Race, Medical Research Distrust, Perceived Harm, and Willingness to Participate in Cardiovascular Prevention Trials. Medicine, Jan 2008 Vol 87(7):1-9

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Novel Study on Minority Participation in Biomedical Research Provides New Insights and Reinforces Recent Findings , Ralph V. Katz, DMD, MPH, PhD, FACE - Posted February 8, 2008

PUBLISHED MANUSCRIPT

Hydrocortisone Therapy for Patients with Septic Shock. NEJM 2008;358:111-24

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Hydrocortisone in severe sepsis: time to accept the null hypothesis?, Robert B. Sanda, MBBS, FRCSI,Omer A. Omer, MD - Posted February 8, 2008

PUBLISHED MANUSCRIPT

Cholesterol Drug Zetia Doesn't Cut Heart Attack Risk. From the News Release by Merck/Schering-Plough. January 14, 2008

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Lowering LDL cholesterol is beneficial: how much, for how long and with which means, remains unclear, Ioanna Gouni-Berthold, M.D. - Posted February 1, 2008

PUBLISHED MANUSCRIPT

Recognition and Management of Diabetic Neuropathy. Journal of Primary Care (Dec 2007); 34(4): 887-913.

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Diabetic Neuropathy: Specialists and Primary Care Physicians in One Boat, Mohsen Eledrisi, MD, FACP, FACE - Posted January 23, 2008

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Obesity and risk of colorectal cancer: a meta-analysis of 31 studies with 70,000 events. Cancer Epidemiology, Biomarkers & Prevention 2007; 16(12): 2533-2547.

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Bowel Cancer and Body Weight: A Definitive Review of the Evidence, Ian Johnson, BSc, PhD - Posted January 23, 2008

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Mediterranean dietary pattern and prediction of all-cause mortality in a US population. Archives of Internal Medicine 2007; 167(22): 2461-2468.

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The Mediterranean Diet Paradigm, Michel de Lorgeril, MD, Patricia Salen, BSc - Posted January 22, 2008

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Abnormal Left Ventricular Longitudinal Functional Reserve in Patients with Diabetes Mellitus: Implication for Detecting Subclinical Myocardial Dysfunction using Exercise Tissue Doppler Echocardiography. Heart 2007;93:1571-1576.

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Diabetic Cardiomyopathy is Common, But How To Best Detect And Manage It Remains Unclear, Stephen M. Twigg, MBBS, PhD, FRACP - Posted January 11, 2008

PUBLISHED MANUSCRIPT

Cardiorespiratory Fitness and Adiposity as Mortality Predictors in Older Adults. JAMA. 2007;298(21):2507-2516.

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Exercise and Aging, Richard D Telford, PhD - Posted January 11, 2008

PUBLISHED MANUSCRIPT

Patients who complete advance directives and what they prefer. Mayo Clin Proc. 2007; 82(12): 1480-1486.

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Breaking Down Barriers to the Completion of Advance Directives, Elizabeth Dobbins, PhD, APRN, BC, CNE - Posted December 21, 2007

PUBLISHED MANUSCRIPT

Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials. American Journal of Clinical Nutrition 2007;86(6):1780-90

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Calcium and Fracture Risk, Ronald C. Hamdy, MD - Posted December 17, 2007

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Use of Intravenous Magnesium to Treat Acute Onset Atrial Fibrillation: A Meta-analysis. Ho KM, Sheridan DJ, Paterson T. Heart 2007;93:1433-1440.

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Use of Magnesium for the Treatment of Acute Onset Atrial Fibrillation, Edmond A Hooker, MD, DrPH - Posted November 9, 2007

PUBLISHED MANUSCRIPT

Sexual Activity and Chronic Heart Failure Mandras SA, Uber PA, Mehra MR. Mayo Clinic Proceedings. 2007;82:1203-1210. Mandras SA, Uber PA, Mehra MR. Mayo Clinic Proceedings. 2007;82:1203-1210.

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Sex and the Heart - More to know about sexual dysfunction in patients with heart failure, Ernst R. Schwarz, MD, PhD, FACC, FESC, FSCAI,Faramarz Tehrani, MD - Posted November 9, 2007

PUBLISHED MANUSCRIPT

Proportion of individuals with low serum vitamin B-12 concentrations without macrocytosis is higher in the post folic acid fortification period than in the pre folic acid fortification period. Wyckoff KF, Ganji V. Am J Clin Nutr. 2007;86(4):1187-92.

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Folic Acid Fortification and the Risk of Masked Vitamin B12 Deficiency, Christopher J. Abularrage, MD - Posted November 9, 2007

PUBLISHED MANUSCRIPT

Gender Differences in Management and Outcomes in Patients with Acute Coronary Syndromes: Results on 20,290 Patients from the AMIS Plus Registry. Radovanovic D, Erne P, Urban P, et al. Heart 2007;93:1369-1375.

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Gender differences in Mortality after Myocardial Infarction: Are there any Differences?, Kimberly P. Chapney, MD,Larry Van-Thomas Crisco, MD,Jack P. Chen, MD, FACC, FSCAI, FCCP - Posted November 9, 2007

PUBLISHED MANUSCRIPT

Topiramate for Treating Alcohol Dependence: A Randomized Controlled Trial. JAMA. 2007;298:1641-1651.

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Topiramate for Treatment of Alcohol Dependence, John B. Standridge, M.D.,Alexander P. Zotos, M.D. - Posted October 30, 2007

PUBLISHED MANUSCRIPT

Conen D, Ridker PM, Burning JE, et al. Risk of Cardiovascular Events Among Women with High Normal Blood Pressure or Blood Pressure Progression: Prospective Cohort Study. BMJ (2007) 335.9: 432-6. BMJ (2007) 335.9: 432-6.

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Cardiovascular Risk in Women with High Normal Blood Pressure. , Amy R. Epps, MD and Terrence X. O’Brien, MD, - Posted October 25, 2007

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Hepner KA, Rowe M, Rost K, et al. The Effect of Adherence to Practice Guidelines on Depression Outcomes. Annals of Internal Medicine (2007) 147.9: 320-329.

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Depression treatment in primary care: Recent improvements leave room to grow, Duncan G. Campbell, PhD - Posted October 1, 2007

PUBLISHED MANUSCRIPT

Conway PH, Cnaan A, Zaoutis T, Henry BV, et al. Recurrent Urinary Tract Infections in Children: Risk Factors and Association with Prophylactic Antimicrobials. JAMA (2007) 298: 179-186

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Is Routine Antimicrobial Prophylaxis Justifiable in Prepubescent Children with Recurrent Urinary Tract Infections?, Marc Smaldone, MD,Danielle Sweeney, MD,Benjamin J. Davies, MD - Posted October 1, 2007

PUBLISHED MANUSCRIPT

Thiazide diuretics directly induce osteoblast differentiation and mineralized nodule formation by interacting with a sodium chloride c-transporter in bone. Dvorak MM, et al. J Am Soc Nephrol 2007;18:2509-16.

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Thiazides and osteoporosis: an addition to the armamentarium?, Ronald C. Hamdy, MD, FRCP, FACP - Posted September 17, 2007

PUBLISHED MANUSCRIPT

Efficacy of a hip protector to prevent hip fracture in nursing home residents. Keil et al: JAMA 2007;298(4):413-22.

SOLICITED RESPONSE(S)

Hip protectors and hip fractures, Ronald C. Hamdy, MD, FRCP, FACP - Posted September 17, 2007

PUBLISHED MANUSCRIPT

Cook, N; Albert, C; Gaziano, M; et al. A Randomized Factorial Trial of Vitamins C and E and Beta Carotene in the Secondary Prevention of Cardiovascular Events in Women. Archives of Internal Medicine. Archives of Internal Medicine. (August 13 2007); 167: 1610-1618.”

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Antioxidant Vitamins - No Benefit for CVD Prevention, Vera Bittner, MD, MSPH - Posted September 11, 2007

PUBLISHED MANUSCRIPT

S Ziaei, M Norrozi, S Faghihzadeh, E Jafarbegloo. A randomised placebo-controlled trial to determine the effect of iron supplementation on pregnancy outcome in pregnant women with haemoglobin. BJOG: (2007) 114, 684–688.

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Iron Supplementation in Pregnancy: More Harm than Good?, Howard A. Shaw, M.D.,Julia A. Shaw, M.D. - Posted September 10, 2007

PUBLISHED MANUSCRIPT

Donohue JM, Cevasco M, Rosenthal M. A decade of direct-to-consumer advertising of prescription drugs. N Eng J Med 2007;357:673-681.

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“And Now a Word from Our Sponsor”…Big Pharma, Christopher K. Finch, PharmD, BCPS,Bob L. Lobo, PharmD, BCPS - Posted September 10, 2007

PUBLISHED MANUSCRIPT

Vlad SC, LaValley MP, McAlindon TE, Felson DT. Glucosamine for pain in osteoarthritis: why do trial results differ? Arth Rheum 2007;56:2267-2277.

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What’s a Clinician to Think? What’s a Clinician to Do?, Dr. Robert R. Johnson, MD, FACP, FACR - Posted September 7, 2007

PUBLISHED MANUSCRIPT

Solomon S, Janardhanan R, Verma A, et al. Effect of angiotensin receptor blockade and antihypertensive drugs on diastolic function in patients with hypertension and diastolic dysfunction: a randomized trial. Lancet 2007;369: 2079-2087.

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Blood Pressure Reduction is More Important than Renin-Angiotensin System Blockade to Improve Diastolic Function, Walter A. Brzezinski, MD,Jan Basile, MD - Posted August 24, 2007

PUBLISHED MANUSCRIPT

Williams SB, Whitlock EP, Edgerton EA et al. Counseling about Proper Use of Motor Vehicle Occupant Restraints and Avoidance of Alcohol Use while Driving: A Systematic Evidence Review for the U.S. Preventive Services Task Force. Ann Int Med. 2007;147:194-206.

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Counseling about Proper Use of Motor Vehicle Occupant Restraints and Avoidance of Alcohol Use while Driving, Juan March MD - Posted August 24, 2007

PUBLISHED MANUSCRIPT

Ingelsson E, Schaefer E, Contois J, et al. Clinical Utility of Different Lipid Measures for Prediction of Coronary Heart Disease in Men and Women. JAMA. 2007; 298: 776-785.

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Do We Need Better Lipid Tools for Cardiovascular Risk Assessment?, Manfredi Rizzo, MD, PhD,Kaspar Berneis, MD - Posted August 20, 2007

PUBLISHED MANUSCRIPT

Iervasi G, Molinaro S, Landi P, et al. Association between increased mortality and mild thyroid dysfunction in cardiac patients. Arch Intern Med 2007;167:1526-1532.

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When the Thyroid is Sick, the Heart is Broken, Shirwan A. Mirza, MD, FACP, FACE - Posted August 17, 2007

PUBLISHED MANUSCRIPT

Dhingra R, Sullivan L, Jacques PF, et al. Soft drink consumption and risk of developing cardiometabolic risk factors and the metabolic syndrome in middle-aged adults in the community. Circulation 2007; 116:480-488.

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Soft Drink Consumption is Associated with an Increased Risk of Metabolic Syndrome and Its Components in Adults, Michael J. Bloch, MD - Posted August 16, 2007

PUBLISHED MANUSCRIPT

Fiore AE, Shay DK, Haber P, et al. MMWR July 13, 2007; 56(RR06);1-54.

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As the 2007-08 Influenza Season Approaches: Highlights of the Advisory Committee on Immunization Practices’ Prevention and Control of Influenza for 2007-08, Keith M. Ramsey, MD - Posted August 15, 2007

PUBLISHED MANUSCRIPT

Datta S, Sternberg M, Johnson R, et al. Gonorrhea and Chlamydia in the United States Among Persons 14 to 39 Years of Age, 1999 to 2002. Annals of Internal Medicine. 2007; 147:2. 89-96.

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Time to Expand Gonorrhea and Chlamydia Screening with Retesting for those with Previously Positive Test Results., Rohit Talwani, MD,Wayne A Duffus, MD PhD - Posted August 9, 2007

PUBLISHED MANUSCRIPT

Meyerovitch J, Rotman-Pikielny P, Sherf M, et al. Serum thyrotropin measurements in the community. Arch Intern Med 2007;167:1533-1538.

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Thyroid Function Test: Thinking Outside the Box (of Guidelines), Shirwan A. Mirza, MD, FACP, FACE - Posted July 31, 2007

PUBLISHED MANUSCRIPT

Effects of Low Habitual Cocoa Intake on Blood Pressure and Bioactive Nitric Oxide: A Randomized Controlled Trial. Taubert D, Roesen R, Lehmann C, et al. JAMA 2007; 298; 49-60

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Chocolate: If It Sounds Too Good To Be True, Be Careful, David T. Nash, MD - Posted July 31, 2007

PUBLISHED MANUSCRIPT

Shah S, Sander S, White C, et al. Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis. The Lancet Infectious Diseases 2007;7:473-480.

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Echinacea Use and the Need for More Studies, Jamal Islam, MD,Susan C. Weller, PhD - Posted July 25, 2007

PUBLISHED MANUSCRIPT

Pettersson A, Richiardi L, Nordenskjold A,et al. Age at surgery for undescended testis and risk of testicular cancer. N Engl J Med 2007 May 3; 356:1835-41.

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Orchiopexy: The Earlier the Better to Decrease Testis Cancer Risk, Ulka Vaishampayan, MD - Posted July 20, 2007

PUBLISHED MANUSCRIPT

Johnson CA, Cen S, Gallaher P, et al. Why Smoking Prevention Programs Sometimes Fail. Does Effectiveness Depend on Sociocultural Context and Individual Characteristics? Can Epid Biom & Prev. 2007; 16:1043-1049.

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Physician-initiated Counseling Regarding Smoking Cessation, Timothy J Barreiro, DO, FCCP, FACOI,David J. Gemmel, Ph.D. - Posted July 18, 2007

PUBLISHED MANUSCRIPT

Marini H, Minutoli L, Polito F et al: Effects of the phytoestrogen genistein on bone metabolism in osteopenic postmenopausal women: a randomized trial. Ann Intern Med 2007; 146:839-847

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Do Phytoestrogens Have a Role in the Management of Postmenopausal Osteoporosis?, E. Michael Lewiecki, MD, FACP, FACE - Posted July 13, 2007

Isoflavones and Bone: More Questions than Answers, Alan Malabanan, MD, FACE - Posted July 16, 2007

PUBLISHED MANUSCRIPT

Mazzone P, Meziane M, Obuchowski N, Ahmad M, Mekhair, T. Lung cancer screening: is it time for a change in policy? Cleveland Clinic Journal of Medicine; 74:

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Lung Cancer Screening: A Clear Voice of Reason, Shea M. Eckardt, MD,Rendell W. Ashton, MD - Posted July 13, 2007

PUBLISHED MANUSCRIPT

Beebe TJ, Johnson CD, Stoner SM, et al. Assessing Attitudes Toward Laxative Preparation in Colorectal Cancer Screening and Effects on Future Testing: Potential Receptivity to Computed Tomographic Colonography. Mayo Clin Proc 2007;82:666-671

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Poor attitudes about preparation, but what’s good for colonoscopy is not good for advanced imaging, S. Bennett Hooks, MD ,Jack A. Di Palma, MD - Posted July 12, 2007

PUBLISHED MANUSCRIPT

Cardiovascular Disease and Subsequent Kidney Disease” by Essam F. Elsayed, MD et al, Arch Intern Med, 2007: 167: 1130-1136.

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Cardiovascular Disease is an Independent Risk Factor for Chronic Kidney Disease, Ivan Monserrate, MD ,Jan N. Basile, MD - Posted July 10, 2007

PUBLISHED MANUSCRIPT

Wright ME, Weinstein SJ, Lawson KA et al. Supplemental and Dietary Vitamin E Intakes and Risk of Prostate Cancer in a Large Prospective Study. Can Epid Biom & Prev. 2007;16: 1128-1135.

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Vitamin E and Prostate Ca, Damian A Laber, MD, FACP - Posted July 9, 2007

PUBLISHED MANUSCRIPT

Ogilvie D, Foster CE, Rothnie H, et al. Interventions to promote walking: systematic review. BMJ 2007;334:1204-1213.

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Walking Works, Dixie L. Thompson, Ph.D., FACSM - Posted July 9, 2007

PUBLISHED MANUSCRIPT

Mayhew E, Ernst E. Acupuncture for fibromyalgia—a systematic review of randomized clinical trials. Rheumatology 2007;46:801-804.

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Is There a Role for Acupuncture in Fibromyalgia?, Victor S. Sierpina, MD - Posted June 28, 2007

PUBLISHED MANUSCRIPT

Okita K, Ichisaka T, Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007 (Nature advance online publication 6 June 2007)

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Recent Advances in Stem Cell Biology, M. William Lensch, Ph.D. - Posted June 27, 2007

PUBLISHED MANUSCRIPT

Holsinger T, Deveau J, Boustani M, Williams JW. Does this patient have dementia?. JAMA 2007;297:2391-2404

SOLICITED RESPONSE(S)

The Diagnosis of Dementia , Ronald C. Hamdy, MD, FRCP, FACP - Posted June 15, 2007

PUBLISHED MANUSCRIPT

Lin J, Manson JE, Lee I-M, et al. Intakes of calcium and vitamin D and breast cancer risk in women. Arch Intern Med 2007; 167:1050-1059.

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Evidence that High Calcium and Vitamin D Intake Decrease the Risk of Breast Cancer in Premenopausal Women: Implications for Breast Cancer Prevention and Screening, Albert S Braverman, MD, FACP - Posted June 12, 2007

PUBLISHED MANUSCRIPT

Nissen SE , Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. New Engl J Med 2007;356.

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The Avandia Debacle: Methodology and Practical Importance of the Findings, Luigi Fernando Meneghini, MD, MBA ,Hermes Florez, MD, MPH, PhD,Leonardo Tamariz MD, MPH - Posted June 12, 2007

Thiazolidinediones and Clinical Diabetes Management: New Challenges for the Summer of 2007, Patrick J. Boyle, MD - Posted June 21, 2007

PUBLISHED MANUSCRIPT

Antipsychotic Drug Use and Mortality in Older Adults with Dementia. Ann Intern Med 2007; 146:775-786

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Antipsychotics in the Elderly, James Wooten, Pharm.D - Posted June 12, 2007

Second-Generation Antipsychotics, Elderly Patients, and Mortality Risk, Leslie Citrome, MD, MPH - Posted June 12, 2007

To Prescribe or Not To Prescribe?: Atypical Antipsychotic Drugs in Patients with Dementia, Dilip V. Jeste, M.D. ,Thomas Meeks, M.D. - Posted June 12, 2007